ZEB1 Antikörper (N-Term)

Produktnummer ABIN2777193

Dieser Anti-ZEB1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von ZEB1 in WB und IHC. Geeignet für Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Schwein und Zebrafisch (Danio rerio). Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für ZEB1 Antikörper (N-Term) (ABIN2777193)

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Schwein, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZEB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ZEB1 Antikörper

Bindungsspezifität: N-Term

Sequenz: NPRRNNVTNY NTVVETNSDS DDEDKLHIVE EESVTDAADC EGVPEDDLPT

Homologie: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ZEB1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZEB1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1124 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ZEB1 Antikörper (ABIN2777193)

Kothandaraman, Bajic, Brendan, Huak, Keow, Razvi, Salto-Tellez, Choolani: "E2F5 status significantly improves malignancy diagnosis of epithelial ovarian cancer." in: BMC cancer, Vol. 10, pp. 64, (2010) (PubMed).

Li, Xia, Huang, Chen, Su, Li, Wang, Ding, Shao: "A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells." in: FEBS letters, Vol. 584, Issue 14, pp. 3198-202, (2010) (PubMed).

Details zu ZEB1

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Andere Bezeichnung: ZEB1

Hintergrund: ZEB1 is a zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start site.
Alias Symbols: AREB6, BZP, DELTA-EF1, FECD6, MGC133261, NIL-2-A, NIL-2A, NIL2A, TCF8, ZEB, ZFHEP, ZFHX1A, PPCD3, DELTAEF1
Protein Interaction Partner: SUMO1, CDK6, GTF2A1, UBR4, SUMO2, SIRT1, SOX2, CTBP2, CTBP1, SMAD7, SMAD6, SMARCA4, SERPINH1, SMAD3, EP300, DRAP1, KAT5, SMAD2, SMAD1, CDH1,
Protein Size: 1124

Molekulargewicht: 124 kDa

Gen-ID: 6935

NCBI Accession: NM_030751, NP_110378

UniProt: P37275

Pathways: Regulation of Muscle Cell Differentiation